Radioprotection of DNA by Glycyrrhizic Acid Through Scavenging free Radicals
نویسندگان
چکیده
منابع مشابه
HESA-A Exerts Its Cytoprotective Effects through Scavenging of Free Radicals: An in Vitro Study
Background: Natural medicines have been recently considered more reasonable for human use most notably due to their safety and tolerance. HESA-A is a marine-originated herbal medicine with a variety of healing effects. However, its exact biological mechanism is not clear. The pre-sent study aimed at the evaluation of the HESA-A antioxidant effect. Methods: Chinese hamster ovary (CHO) an...
متن کاملScavenging Effects of Dexrazoxane on Free Radicals
Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron, thus preventing iron-based oxygen radical formation. However, it is not known whether the antiox...
متن کاملhesa-a exerts its cytoprotective effects through scavenging of free radicals: an in vitro study
background: natural medicines have been recently considered more reasonable for human use most notably due to their safety and tolerance. hesa-a is a marine-originated herbal medicine with a variety of healing effects. however, its exact biological mechanism is not clear. the pre-sent study aimed at the evaluation of the hesa-a antioxidant effect. methods: chinese hamster ovary (cho) and human ...
متن کاملMechanism of Calf thymus DNA radioprotection by sucrose: A combined effect of scavenging action and altered water
Background: Development of safe radioprotector is a challenging task. In this study radioprotective effect of sucrose has been demonstrated in calf thymus DNA (CtDNA). Sucrose is a free radical scavenger and also acts as osmolyte and therefore can influence the water activity around DNA and effects of radiation on DNA. Hoechst 33258 was used to probe the possible alteration in physicochemical p...
متن کاملFree radical scavenging and metal chelation by Tinospora cordifolia, a possible role in radioprotection.
Aqueous extract of T. cordifolia inhibited Fenton (FeSO4) reaction and radiation mediated 2-deoxyribose degradation in a dose dependent fashion with an IC50 value of 700 microg/ml for both Fenton and radiation mediated 2-DR degradation. Similarly, it showed a moderate but dose dependent inhibition of chemically generated superoxide anion at 500 microg/ml concentration and above with an IC50 val...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2004
ISSN: 0449-3060
DOI: 10.1269/jrr.45.461